I did as it said and ran:
/usr/local/cpanel/scripts/check_cpanel_rpms --fix
Seems to have "fixed" it.
[2021-08-21 07:27:14 -0400] The following files were found to be altered from their original RPM:
[2021-08-21 07:27:14 -0400] cpanel-clamav-virusdefs,0.101.5,5.cp1198
[2021-08-21 07:27:14 -0400]
[2021-08-21 07:27:14 -0400] Removing 1 broken rpms: cpanel-clamav-virusdefs-0.101.5-5.cp1198.x86_64
[2021-08-21 07:27:14 -0400] Maximum sync children set to 16 based on 24469M available memory.
[2021-08-21 07:27:14 -0400] Downloading
http://httpupdate.cpanel.net/RPM/11.98/centos/8/x86_64/sha512
[2021-08-21 07:27:15 -0400] Successfully verified signature for cpanel (key types: release).
[2021-08-21 07:27:15 -0400] Downloading
http://httpupdate.cpanel.net/RPM/11...-clamav-virusdefs-0.101.5-5.cp1198.x86_64.rpm
[2021-08-21 07:27:44 -0400] Disabling service monitoring.
[2021-08-21 07:27:44 -0400] Hooks system enabled.
[2021-08-21 07:27:44 -0400] Checking for and running RPM::Versions 'pre' hooks for any Packages about to be installed
[2021-08-21 07:27:44 -0400] All required 'pre' hooks have been run
[2021-08-21 07:27:44 -0400] No packages need to be uninstalled
[2021-08-21 07:27:44 -0400] Installing new rpms: cpanel-clamav-virusdefs-0.101.5-5.cp1198.x86_64.rpm
[2021-08-21 07:27:44 -0400] Verifying packages...
[2021-08-21 07:27:45 -0400] Preparing packages...
[2021-08-21 07:27:45 -0400] cpanel-clamav-virusdefs-0.101.5-5.cp1198.x86_64
[2021-08-21 07:27:47 -0400] Hooks system enabled.
[2021-08-21 07:27:47 -0400] Checking for and running RPM::Versions 'post' hooks for any Packages about to be installed
[2021-08-21 07:27:47 -0400] All required 'post' hooks have been run
[2021-08-21 07:27:47 -0400] Restoring service monitoring.